Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 13/20 | 0.52 |
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.45 |
| ▸ | S100A10 | P60903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243692 | 0.90 | KDM4E (0.49) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL6237553 | 0.84 | KDM4E (0.48) | ALDH1A1DRD4KDM4ETDP1MAPT | |
| SCHEMBL3999430 | 0.80 | KDM4E (0.67) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL7247601 | 0.79 | KMT2A (0.51) | ALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL4005384 | 0.77 | DRD4 (0.63) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL4009446 | 0.77 | ALDH1A1 (0.58) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL4005440 | 0.76 | ALDH1A1 (0.60) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL4008666 | 0.76 | DRD4 (0.61) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL4002936 | 0.75 | ALDH1A1 (0.59) | ALDH1A1DRD4DRD2DRD3KDM4E | |
| SCHEMBL6236477 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |