Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237553 | 0.81 | KDM4E (0.48) | ALDH1A1KDM4EMAPTLMNACYP2D6 | |
| SCHEMBL4004441 | 0.79 | ALDH1A1 (0.65) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL6243692 | 0.78 | KDM4E (0.49) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL7247601 | 0.76 | KMT2A (0.51) | ALDH1A1POLBKDM4EMAPTLMNA | |
| SCHEMBL6243192 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EMAPTCYP2C19TSHR | |
| SCHEMBL6246218 | 0.74 | POLB (0.41) | ALDH1A1POLB | |
| SCHEMBL7097274 | 0.72 | ALDH1A1 (0.49) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL18657481 | 0.69 | ACHE (0.84) | ALDH1A1POLBL3MBTL1KDM4EMAPT | |
| SCHEMBL6245789 | 0.68 | CA1 (0.41) | POLBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL8288257 | 0.66 | ALDH1A1 (0.65) | ALDH1A1POLBL3MBTL1KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |