Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553688 | 0.82 | MEN1 (0.52) | HPGDMEN1KMT2AHCAR3BRD4 | |
| SCHEMBL18250746 | 0.76 | MAPT (0.46) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18250241 | 0.74 | MAPT (0.45) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5768114 | 0.73 | HDAC1 (0.55) | ALDH1A1HPGDHCAR3 | |
| SCHEMBL6285546 | 0.72 | F10 (0.42) | ALDH1A1HPGDHCAR3 | |
| SCHEMBL12053166 | 0.72 | HPGD (0.38) | ALDH1A1HPGDCNR2CNR1BCHE | |
| SCHEMBL12053612 | 0.72 | CNR2 (0.45) | HPGDCNR2CNR1BCHEACHE | |
| SCHEMBL3436680 | 0.70 | HCAR3 (0.58) | ALDH1A1HPGDHCAR3 | |
| SCHEMBL6112850 | 0.70 | HPGD (0.57) | ALDH1A1HPGDKMT2AHCAR3 | |
| SCHEMBL30138443 | 0.70 | HCAR3 (0.58) | ALDH1A1HPGDHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461035-A4 | SUBSTITUTED 2-METHYL-BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1461035-A2 | SUBSTITUTED 2-METHYL-BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | Bristol-Myers Squibb Company (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053344-A2 | SUBSTITUTED 2-METHYL-BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |