SCHEMBL6244231

SCHEMBL6244231

NC(=O)/C=C/c1cccc(F)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.61
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
PTGS1 P23219 2/20 0.53
PTGS2 P35354 1/20 0.53
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
NQO2 P16083 1/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 1/20 0.51
XBP1 P17861 1/20 0.51
KMT2A Q03164 1/20 0.51
MMP1 P03956 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1380347 1.00 NFE2L2 (0.61) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL4398128 0.86 NPSR1 (0.55) MAOBPTGS1PTGS2SMN1; SMN2ALDH1A1
SCHEMBL5598783 0.85 NFE2L2 (0.65) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL5598785 0.85 NFE2L2 (0.65) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL79651 0.83 NFE2L2 (0.63) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL30337035 0.83 NFE2L2 (0.63) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL27674511 0.83 NFE2L2 (0.63) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL79650 0.83 NFE2L2 (0.63) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL7654865 0.83 NFE2L2 (0.63) NFE2L2MAOAMAOBPTGS1PTGS2
SCHEMBL2825728 0.82 NFE2L2 (0.56) NFE2L2MAOBPTGS1PTGS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1217943-C New use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2005-09-07 CN claimed
EP-1067113-B1 Process for the preparation of phenethylamines and intermediates therefor LANXESS DEUTSCHLAND GMBH (DE) 2005-07-20 EP claimed
CN-1423651-A Novel use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2003-06-11 CN claimed
EP-4623015-A1 POLYMER WITH LOW MOLECULAR WEIGHT PORTION AND HIGH GLASS TRANSITION TEMPERATURE PORTION FOR EARLY BLOCK RESISTANCE Benjamin Moore & Co. (US) 2025-10-01 EP disclosed
US-12404397-B2 Polymer with low molecular weight portion and high glass transition temperature portion for early block resistance COLUMBIA INSURANCE COMPANY (US) 2025-09-02 US disclosed
US-12404358-B2 Hydrophobic, low glass transition temperature oligomer with chain transfer agent COLUMBIA INSURANCE COMPANY (US) 2025-09-02 US disclosed
EP-4543993-A1 NONIONIC RESINS, AND MIXTURES OF NONIONIC RESINS WITH CATIONIC ADDITIVES FOR STAIN BLOCKING ARCHITECTURAL COMPOSITIONS Benjamin Moore & Co. (US) 2025-04-30 EP disclosed
EP-4543994-A1 NONIONIC RESINS AND THEIR USES IN STAIN BLOCKING ARCHITECTURAL COMPOSITIONS Benjamin Moore & Co. (US) 2025-04-30 EP disclosed
EP-4543992-A1 STAIN BLOCKING ARCHITECTURAL COMPOSITIONS WITH CATIONIC RESIN AND NONIONIC RESIN BLENDS Benjamin Moore & Co. (US) 2025-04-30 EP disclosed
US-20240409766-A1 NONIONIC RESINS, AND MIXTURES OF NONIONIC RESINS WITH CATIONIC ADDITIVES FOR STAIN BLOCKING ARCHITECTURAL COMPOSITIONS COLUMBIA INSURANCE CO (US) 2024-12-12 US disclosed
US-20240384124-A1 STAIN BLOCKING ARCHITECTURAL COMPOSITIONS WITH CATIONIC RESIN AND NONIONIC RESIN BLENDS COLUMBIA INSURANCE CO (US) 2024-11-21 US disclosed
CN-1217943-C New use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2005-09-07 CN disclosed
EP-1067113-B1 Process for the preparation of phenethylamines and intermediates therefor LANXESS DEUTSCHLAND GMBH (DE) 2005-07-20 EP disclosed
CN-1423651-A Novel use and novel N-azabicyclo-amide derivatives ASTRAZENECA AB (SE) 2003-06-11 CN disclosed
US-6255528-B1 REACTING AN ALKYLFLUOROBROMOBENZENE OR FLUOROBROMOBENZENE WITH ACRYLAMIDE IN PRESENCE OF PALLADIUM CATALYST, HYDROGENATING THE RESULTING ARYLACRYLAMIDE, AND THEN REARRANGING IT LANXESS DEUTSCHLAND GMBH (DE) 2001-07-03 US disclosed
EP-1067113-A2 Process for the preparation of phenethylamines and intermediates therefor BAYER AG (DE) 2001-01-10 EP disclosed
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
CN-1049224-C Polymers as alignment layer ROLIC AG (CH) 2000-02-09 CN disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed
CN-1091458-A Polymkeric substance as oriented layer HOFFMANN LA ROCHE (CH) 1994-08-31 CN disclosed