Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | TNKS | O95271 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.61 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654865 | 1.00 | NFE2L2 (0.63) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| SCHEMBL79651 | 1.00 | NFE2L2 (0.63) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| SCHEMBL30337035 | 1.00 | NFE2L2 (0.63) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| Guanidine SCHEMBL7159047 | 0.90 | NPSR1 (0.57) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| Guanidine SCHEMBL7159042 | 0.90 | NPSR1 (0.57) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| SCHEMBL27746163 | 0.87 | NFE2L2 (0.57) | NFE2L2NPSR1HDAC3HDAC4HDAC1 | |
| SCHEMBL5598783 | 0.86 | NFE2L2 (0.65) | NFE2L2MMP1MMP2MMP9MAOA | |
| SCHEMBL5598785 | 0.86 | NFE2L2 (0.65) | NFE2L2MMP1MMP2MMP9MAOA | |
| SCHEMBL271386 | 0.86 | NPSR1 (0.74) | NPSR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL69146 | 0.86 | NPSR1 (0.74) | NPSR1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| US-12497636-B2 | Recombinant Saccharomyces cerevisiae cells for cannabinoid production | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-12-16 | — | — | US | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118027276-A | Multipolymer, preparation method and application thereof, negative electrode slurry, negative electrode plate and lithium ion battery | 北京卫蓝新能源科技有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-109824294-B | High-strength stable liquid accelerator and preparation method thereof | 科之杰新材料集团有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-108690609-B | Synthesis method of water-soluble or oil-soluble carbon dots and fluorescent carbon dots | 中国科学院理化技术研究所 | 2021-05-14 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| EP-1526584-B1 | Method of forming electroluminescent semiconducting nanocrystal patterned layer for an organic-inorganic hybrid electroluminescent devices, and organic-inorganic hybrid electroluminescent device using the same. | SAMSUNG ELECTRONICS CO LTD (KR) | 2017-06-14 | — | — | EP | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-20060020141-A1 | Metallized dye | XEROX CORPORATION | 2006-01-26 | — | — | US | claimed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| WO-2005102503-A1 | PERVAPORATION COMPOSITE MEMBRANES | MCMASTER UNIVERSITY (CA) | 2005-11-03 | — | — | WO | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050161666-A1 | Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-07-28 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| EP-1526584-A2 | Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same | Samsung Electronics Co., Ltd (KR) | 2005-04-27 | — | — | EP | claimed |
| EP-1085095-A1 | Synthesis of optically active phenylalanine analogs through microbial transformations | NSC Technologies Company, L.L.C. (US) | 2001-03-21 | — | — | EP | claimed |
| US-5985927-A | Medicaments for the selective treatment of tumor tissues | KREUTZ WERNER (DE) | 1999-11-16 | — | — | US | claimed |
| US-5981239-A | USING LYASE FROM RHODOTORULA TO INTRODUCE AMMONIA STEREOSPECIFICALLY INTO DOUBLE BOND OF AN ARYLACRYLIC ACID; AMINO ACID FOR USE IN VIRICIDAL PROTEASE INHIBITORS AGAINST HUMAN IMMUNODEFICIENCY VIRUS, INFLUENZA AND OTHERS | GREAT LAKES CHEMICAL CORP. (US) | 1999-11-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | NFE2L2 4821/4885NPSR1 3502/4885HDAC3 3090/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | NFE2L2 4821/4885NPSR1 3502/4885HDAC3 3090/4885 |
| US-20060020141-A1 | Metallized dye | CDYL, CDY1; CDY1B, CDYL2 | NFE2L2 1266/4885NPSR1 2989/4885HDAC3 1033/4885 |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | NFE2L2 3435/4885NPSR1 3033/4885HDAC3 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.