Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242662 | 0.86 | FFAR1 (0.64) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL6238462 | 0.85 | FFAR1 (0.70) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL1747337 | 0.84 | FFAR1 (0.77) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL6242343 | 0.83 | FFAR1 (0.60) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL6163614 | 0.82 | MAPT (0.69) | MAPTALDH1A1FAAHMEN1POLB | |
| SCHEMBL13918253 | 0.80 | FFAR1 (0.61) | FFAR1MAPTALDH1A1PPARDADAMTS5 | |
| SCHEMBL6238338 | 0.80 | FFAR1 (0.66) | FFAR1FFAR4PTGER1PTGER4PTGER3 | |
| SCHEMBL810045 | 0.79 | RAB9A (0.63) | FFAR1FFAR4MAPTALDH1A1MEN1 | |
| Benzene SCHEMBL28258789 | 0.78 | ALOX15 (0.63) | MAPTALDH1A1PPARDFAAHMEN1 | |
| SCHEMBL27718811 | 0.78 | FFAR1 (0.62) | FFAR1FFAR4PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |