Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242169 | 0.82 | ALDH1A1 (0.43) | HSP90AA1TSHRHPGDALDH1A1KDM4E | |
| SCHEMBL11871033 | 0.77 | VCAM1 (0.51) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7683236 | 0.76 | MEN1 (0.44) | KMT2AMEN1HSP90AA1TSHRSMN1; SMN2 | |
| SCHEMBL6244108 | 0.76 | KMT2A (0.52) | KMT2AMEN1LMNAHSP90AA1TSHR | |
| SCHEMBL6246280 | 0.76 | HSP90AA1 (0.43) | KMT2AMEN1HSP90AA1TSHRUSP2 | |
| SCHEMBL3822620 | 0.75 | HSP90AA1 (0.61) | KMT2ALMNAHSP90AA1USP2HPGD | |
| SCHEMBL12483596 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1LMNAHSP90AA1HPGD | |
| SCHEMBL14882786 | 0.74 | KDM4E (0.56) | LMNAHSP90AA1SMN1; SMN2USP2HPGD | |
| SCHEMBL937394 | 0.73 | ALDH1A1 (0.57) | KMT2AMEN1LMNATSHRSMN1; SMN2 | |
| SCHEMBL6245778 | 0.72 | HSP90AA1 (0.44) | KMT2AMEN1LMNAHSP90AA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030709-A1 | NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE | LG LIFE SCIENCES LTD. (KR) | 2005-04-07 | — | — | WO | disclosed |