Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | PGR | P06401 | 5/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246691 | 1.00 | NR3C1 (0.63) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL11321384 | 0.87 | NR3C1 (0.78) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL5262257 | 0.83 | CYP3A4 (0.58) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL5262259 | 0.83 | CYP3A4 (0.58) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL5654602 | 0.83 | CYP3A4 (0.58) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL6246699 | 0.82 | CYP3A4 (0.48) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL5652888 | 0.82 | CYP3A4 (0.48) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL6241909 | 0.82 | CYP3A4 (0.48) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL6241705 | 0.81 | KDM4E (0.46) | NR3C1LMNAPGRHIF1ACYP3A4 | |
| SCHEMBL6241434 | 0.81 | KDM4E (0.46) | NR3C1LMNAPGRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207165-B1 | Isomerisation of 6beta-fluorosteroids into the corresponding 6alpha-fluoro derivatives | FARMABIOS SPA (IT) | 2005-07-20 | — | — | EP | disclosed |
| EP-1207165-A2 | Isomerisation of 6beta-fluorosteroids into the corresponding 6alpha-fluoro derivatives | Farmabios S.r.l. (IT) | 2002-05-22 | — | — | EP | disclosed |
| US-6369218-B1 | REACTION WITH ORGANIC BASE CONTAINING DIAZOIMINO GROUP IN APROTIC POLAR SOLVENT | FARMABIOS S.R.L (IT) | 2002-04-09 | — | — | US | disclosed |