Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | PYGL | P06737 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NHERF1 | O14745 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245333 | 0.82 | HDAC2 (0.42) | HDAC2PYGLKDM4ENPC1MAPT | |
| SCHEMBL6242347 | 0.81 | KDM4E (0.39) | HDAC2PYGLKDM4ENPC1MAPT | |
| SCHEMBL6248210 | 0.76 | NPC1 (0.39) | HDAC2PYGLKDM4ENPC1MAPT | |
| SCHEMBL5733235 | 0.76 | HDAC2 (0.47) | HDAC2PYGLNHERF1TP53POLB | |
| SCHEMBL6178778 | 0.74 | KDM4E (0.61) | KDM4ENPC1MAPTTP53 | |
| SCHEMBL6180022 | 0.67 | KMT2A (0.43) | HDAC2PYGLKDM4ENPC1MAPT | |
| SCHEMBL5734157 | 0.66 | TP53 (0.42) | KDM4ENPC1MAPTTP53 | |
| Centanamycin SCHEMBL29441389 | 0.65 | LMNA (0.46) | KDM4EMAPTTP53POLB | |
| Centanamycin SCHEMBL5733476 | 0.65 | LMNA (0.46) | KDM4EMAPTTP53POLB | |
| SCHEMBL6242344 | 0.63 | KDM4E (0.38) | HDAC2PYGLKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320522-B1 | COMPOSITIONS AND METHODS OF THE USE THEREOF ACHIRAL ANALOGUES OF CC-1065 AND THE DUOCARMYCINS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-11-23 | — | — | EP | claimed |