Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802473 | 0.82 | OPRM1 (0.47) | ADRB2ALDH1A1HTTGRIN1GRIN2A | |
| SCHEMBL6798038 | 0.80 | OPRM1 (0.40) | ADRB2ALDH1A1HTTGRIN1GRIN2A | |
| SCHEMBL6801870 | 0.76 | GAA (0.40) | ALDH1A1GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL6801866 | 0.76 | GAA (0.40) | ALDH1A1GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL15863115 | 0.76 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2BOPRM1HSD11B1 | |
| SCHEMBL6803003 | 0.74 | DPP4 (0.52) | GRIN1GRIN2AGRIN2BOPRM1KDM4E | |
| SCHEMBL28459324 | 0.74 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BOPRM1HSD11B1 | |
| SCHEMBL6182607 | 0.74 | DPP4 (0.52) | GRIN1GRIN2AGRIN2BOPRM1KDM4E | |
| SCHEMBL27459789 | 0.74 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BOPRM1HSD11B1 | |
| SCHEMBL7906825 | 0.74 | ESR1 (0.53) | ADRB2ALDH1A1HTTHSD11B1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501800-A1 | BOMBESIN ANTAGONISTS | Warner-Lambert Company LLC (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003092670-A1 | BOMBESIN ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-13 | — | — | WO | disclosed |