Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182607 | 1.00 | DPP4 (0.52) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL20777704 | 0.98 | DPP4 (0.53) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL11972618 | 0.95 | DPP4 (0.48) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL3892446 | 0.91 | MAOA (0.50) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL8627195 | 0.86 | GRIN1 (0.47) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL21927029 | 0.83 | ALDH1A1 (0.43) | DPP4GRIN1GRIN2AGRIN2BSLC6A3 | |
| SCHEMBL27459789 | 0.82 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BSLC6A3SLC6A4 | |
| SCHEMBL28459324 | 0.82 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BOPRM1KDM4E | |
| SCHEMBL3326134 | 0.80 | PTPN11 (0.47) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 | |
| SCHEMBL15863115 | 0.80 | GRIN1 (0.47) | GRIN1GRIN2AGRIN2BOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | DPP4 1446/4885GRIN1 780/4885GRIN2A 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.