SCHEMBL624540

SCHEMBL624540

CC(=O)CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
CA12 O43570 2/20 0.68
CA9 Q16790 2/20 0.68
MAPT P10636 2/20 0.58
KDM4E B2RXH2 1/20 0.58
RAB9A P51151 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GSK3B P49841 1/20 0.54
NPC1 O15118 1/20 0.54
CA2 P00918 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
ELANE P08246 1/20 0.53
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29448333 1.00 ALDH1A1 (0.69) ALDH1A1CA12CA9MAPTKDM4E
Ethylene SCHEMBL9096059 0.96 ALDH1A1 (0.70) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL20876339 0.85 ALDH1A1 (0.71) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL4681571 0.85 ALDH1A1 (0.71) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL10671092 0.83 ALDH1A1 (0.59) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL14282655 0.83 ALDH1A1 (0.50) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL8940040 0.83 CA12 (0.73) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL1274905 0.82 ALDH1A1 (1.00) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL29744481 0.81 CA12 (1.00) ALDH1A1CA12CA9MAPTKDM4E
SCHEMBL11148327 0.81 CA12 (0.70) ALDH1A1CA12CA9MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
WO-2025264954-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-12-26 WO disclosed
US-20250340560-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BEIGENE SWITZERLAND GMBH (CH) 2025-11-06 US disclosed
US-20250276976-A1 CARDIAC SARCOMERE INHIBITORS CYTOKINETICS, INC. 2025-09-04 US disclosed
US-12384790-B2 Pteridinone compounds and uses thereof VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-08-12 US disclosed
EP-4585265-A2 HETEROARYL INHIBITORS OF PLASMA KALLIKREIN Takeda Pharmaceutical Company Limited (JP) 2025-07-16 EP disclosed
US-12275741-B2 Cardiac sarcomere inhibitors CYTOKINETICS, INC. (US) 2025-04-15 US disclosed
US-20240382482-A1 PLASMA KALLIKREIN INHIBITORS TAKEDA PHARMACEUTICALS CO (JP) 2024-11-21 US disclosed
US-20240368172-A1 CARDIAC SARCOMERE INHIBITORS CYTOKINETICS, INC. 2024-11-07 US disclosed
US-20240254128-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BEIGENE SWITZERLAND GMBH (CH) 2024-08-01 US disclosed
EP-0254245-B1 Hetrazepins and processes for their preparation BOEHRINGER INGELHEIM KG (DE) 1994-09-28 EP disclosed
US-5211738-A ADENINE DERIVATIVES AND THEIR USE AS A PLANT GROWTH REGULATOR MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1993-05-18 US disclosed
US-5190589-A Compounds and process preparing a substituted or an unsubstituted 4(5)-(ω-aminoalkyl)imidazole CEDONA PHARMACEUTICALS B.V. (NL) 1993-03-02 US disclosed
EP-0508777-A2 Novel adenine derivatives and their use as plant growth regulators MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-10-14 EP disclosed
EP-0415948-A1 PROCESS FOR PREPARING A SUBSTITUTED OR AN UNSUBSTITUTED 4(5)-($g(v)-AMINOALKYL)IMIDAZOLE CEDONA PHARMACEUTICALS B.V. (NL) 1991-03-13 EP disclosed
WO-1989010360-A1 PROCESS FOR PREPARING A SUBSTITUTED OR AN UNSUBSTITUTED 4(5)-(omega-AMINOALKYL)IMIDAZOLE CEDONA PHARMACEUTICALS B.V. (NL) 1989-11-02 WO disclosed
US-RE32868-E Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1989-02-14 US disclosed
EP-0254245-A1 Hetrazepins and processes for their preparation BOEHRINGER INGELHEIM KG (DE) 1988-01-27 EP disclosed
US-4395417-A Antihyperlipidemic compositions RESEARCH CORPORATION (US) 1983-07-26 US disclosed
US-3992408-A CHEMICAL INTERMEDIATES THE UPJOHN COMPANY (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254128-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BTK, LCK, SYK ALDH1A1 3106/4885CA12 4885/4885CA9 4847/4885
US-12275741-B2 Cardiac sarcomere inhibitors TNNI3, MYLK2, TNNT2 ALDH1A1 3517/4885CA12 4807/4885CA9 4613/4885
US-20240382482-A1 PLASMA KALLIKREIN INHIBITORS KLKB1, KLK5, KLK1 ALDH1A1 3175/4885CA12 1813/4885CA9 1004/4885
US-20240368172-A1 CARDIAC SARCOMERE INHIBITORS TNNI3, MYLK2, TNNT2 ALDH1A1 3517/4885CA12 4807/4885CA9 4613/4885
US-20250276976-A1 CARDIAC SARCOMERE INHIBITORS TNNI3, MYLK2, TNNT2 ALDH1A1 3517/4885CA12 4807/4885CA9 4613/4885
US-12384790-B2 Pteridinone compounds and uses thereof DPYD, PKD1, TYMP ALDH1A1 569/4885CA12 4350/4885CA9 2534/4885
US-20250340560-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS BTK, LCK, SYK ALDH1A1 3106/4885CA12 4885/4885CA9 4847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.