SCHEMBL624570

SCHEMBL624570

C=CCc1cccc(P)c1CC=C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.47
GABRB2 P47870 2/20 0.47
AKR1B1 P15121 1/20 0.37
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
MAPT P10636 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 3/20 0.33
GAA P10253 3/20 0.33
LMNA P02545 2/20 0.33
MTNR1A P48039 1/20 0.33
KDM4E B2RXH2 2/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
ALOX12 P18054 1/20 0.31
AURKA O14965 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7610470 0.98 GABRA1 (0.46) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL18136 0.84 GABRA1 (0.56) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL1326258 0.81 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL170640 0.80 GABRA1 (0.47) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL2362269 0.78 GABRA1 (0.61) GABRA1GABRB2AKR1B1KMT2AMEN1
Bromide SCHEMBL28443429 0.78 GABRA1 (0.45) GABRA1GABRB2AKR1B1KMT2AMEN1
Hydrochloric Acid SCHEMBL3265432 0.78 GABRA1 (0.45) GABRA1GABRB2AKR1B1L3MBTL1ALDH1A1
SCHEMBL4170461 0.78 GABRA1 (0.50) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL12076599 0.78 GABRA1 (0.54) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL10625097 0.77 GABRA1 (0.48) GABRA1GABRB2AKR1B1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774959-B1 ISOBUTYLENE-BASED POLYMERS WITH OLEFINIC SIDE CHAIN SUBSTITUENTS AND CURABLE COMPOSITIONS CONTAINING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-02-12 EP claimed
US-12043729-B2 Isobutylene-based polymers with olefinic side chain substituents and curable compositions containing the same ExxonMobil Engineering & Technology Company (US) 2024-07-23 US claimed
CN-117443456-B Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-04-05 CN claimed
CN-117443456-A Rhodium-phosphine catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-26 CN claimed
CN-112135848-B Isobutylene-based polymers having olefinic side chain substituents and curable compositions containing the same 埃克森美孚化学专利公司 2023-08-29 CN claimed
EP-3610327-B1 METHOD OF IMPROVING LIGHT STABILITY OF FLEXOGRAPHIC PRINTING PLATES FEATURING FLAT TOP DOTS MACDERMID GRAPHICS SOLUTIONS LLC (US) 2023-03-22 EP claimed
CN-109407470-B Method for improving surface curing in digital flexographic printing plates 麦克德米德图像方案股份有限公司 2021-10-08 CN claimed
CN-108885392-B Method for improving light stability of flexographic printing plates characterized by flat-top dots 麦克德米德图像方案股份有限公司 2021-09-14 CN claimed
US-11117913-B2 Tridentate iminopyrrolyl nickel complexes and their use as catalysts for the reaction of polymerisation of ethylene to hyperbranched polyethylene INSTITUTO SUPERIOR TÉCNICO (PT) 2021-09-14 US claimed
US-11013133-B2 Electronic devices comprising butyl rubber ARLANXEO Singapore Pte. Ltd (SG) 2021-05-18 US claimed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO claimed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO claimed
US-6007967-A Methods for off-contact imaging solid printing plates POLYFIBRON TECHNOLOGIES, INC. (US) 1999-12-28 US claimed
EP-0958279-A1 CATALYST COMPOSITIONS AND PROCESSES FOR OLEFIN POLYMERS AND COPOLYMERS Cryovac, Inc. (US) 1999-11-24 EP claimed
EP-0917529-A1 CATALYST COMPOSITIONS AND PROCESSES FOR OLEFIN OLIGOMERIZATION AND POLYMERIZATION Cryovac, Inc. (US) 1999-05-26 EP claimed
WO-1998042664-A1 CATALYST COMPOSITIONS AND PROCESSES FOR OLEFIN POLYMERS AND COPOLYMERS CRYOVAC, INC. (US) 1998-10-01 WO claimed
WO-1998042665-A1 CATALYST COMPOSITIONS AND PROCESSES FOR OLEFIN OLIGOMERIZATION AND POLYMERIZATION CRYOVAC, INC. (US) 1998-10-01 WO claimed
EP-0322811-B1 Process for producing aldehydes or mixtures of ketones and aldehydes UNION CARBIDE CORP (US) 1993-11-10 EP claimed
US-4892944-A Process for producing quaternary salts MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-01-09 US claimed
US-3992322-A Preparation of polymerization catalyst systems UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-11-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11117913-B2 Tridentate iminopyrrolyl nickel complexes and their use as catalysts for the reaction of polymerisation of ethylene to hyperbranched polyethylene PCNA, PARN, PARG GABRA1 3414/4885GABRB2 3427/4885AKR1B1 4414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.