Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984795 | 0.78 | ENPEP (0.35) | ENPEPPMP22NLRP3S1PR2S1PR1 | |
| SCHEMBL820427 | 0.76 | LMNA (0.52) | ENPEPS1PR2S1PR1S1PR3GABRR1 | |
| SCHEMBL7436774 | 0.76 | PMP22 (0.38) | ENPEPPMP22NLRP3KMT2AS1PR2 | |
| SCHEMBL29180212 | 0.76 | PMP22 (0.38) | ENPEPPMP22NLRP3KMT2AS1PR2 | |
| SCHEMBL9930127 | 0.76 | ENPEP (0.59) | ENPEP | |
| SCHEMBL14851180 | 0.76 | ENPEP (0.34) | ENPEPPMP22NLRP3 | |
| SCHEMBL15980693 | 0.74 | ANPEP (0.41) | ENPEPPMP22NLRP3 | |
| SCHEMBL28378901 | 0.74 | ENPEP (0.63) | ENPEPPMP22 | |
| SCHEMBL28914371 | 0.74 | LMNA (0.50) | ENPEPS1PR2S1PR1S1PR3 | |
| SCHEMBL14737979 | 0.73 | PLA2G2C (0.33) | ENPEPPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361880-B1 | 6-SUBSTITUTED PYRIDO-PYRIMIDINES | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | EP | disclosed |