Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498326 | 0.90 | PIM1 (0.48) | CETPMAPTPIM1PIM2SMN1; SMN2 | |
| SCHEMBL13019852 | 0.85 | LMNA (0.44) | CETPMAPTPIM1PIM2SMN1; SMN2 | |
| SCHEMBL1526052 | 0.82 | NPC1 (0.53) | ACHEMAPTCA1CA2CA7 | |
| SCHEMBL3278206 | 0.81 | CETP (0.52) | CETPACHEALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13064202 | 0.80 | TP53 (0.49) | CETPALDH1A1CYP3A4L3MBTL1PIM1 | |
| SCHEMBL3128057 | 0.80 | ACHE (0.48) | ACHEMAPTCA1CA2CA7 | |
| SCHEMBL12403373 | 0.79 | CA1 (0.50) | ACHEMAPTCA1CA2CA7 | |
| SCHEMBL9169333 | 0.79 | PIM1 (0.42) | CETPMAPTHCRTR1HCRTR2PIM1 | |
| SCHEMBL5670119 | 0.79 | CETP (0.54) | CETPMAOBTSHR | |
| SCHEMBL13144294 | 0.78 | CETP (0.52) | CETPPIM1PIM2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| EP-1266902-B1 | Process for the preparation of polyfluoroalkyl lithium compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-6872861-B2 | Process for preparing polyfluoroalkylithium compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-29 | — | — | US | disclosed |
| US-20030065135-A1 | Process for preparing polyfluoroalkyllithium compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2003-04-03 | — | — | US | disclosed |
| EP-1266902-A1 | Process for the preparation of polyfluoroalkyl lithium compounds | BAYER AG (DE) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | CETP 1906/4885ACHE 2/4885MAPT 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.