Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411118 | 0.80 | GFER (0.46) | ARGFERNR1I2SMARCA2SMARCA4 | |
| SCHEMBL14398088 | 0.78 | SMN1; SMN2 (0.42) | ARSMN1; SMN2KMT2AMEN1ATM | |
| SCHEMBL2555259 | 0.77 | AR (0.52) | ARGFERKMT2AMEN1ATM | |
| SCHEMBL3220834 | 0.76 | ALDH1A1 (0.50) | LMNASMN1; SMN2CSF1RMAPTKMT2A | |
| SCHEMBL23043568 | 0.76 | PBRM1 (0.54) | ARGFERACHEBCHENR1I2 | |
| SCHEMBL2107135 | 0.76 | BCHE (0.47) | ARGFERACHEBCHENR1I2 | |
| SCHEMBL29512584 | 0.76 | PBRM1 (0.54) | ARGFERACHEBCHENR1I2 | |
| SCHEMBL406932 | 0.75 | AR (0.43) | ARGFERNR1I2SMARCA2SMARCA4 | |
| SCHEMBL31167266 | 0.74 | KEAP1 (0.52) | LMNASMN1; SMN2CSF1RMAPTKMT2A | |
| SCHEMBL28452171 | 0.74 | KEAP1 (0.52) | LMNASMN1; SMN2CSF1RMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205218-B | Photo-initiated aldehyde removal method | 广州中医药大学(广州中医药研究院) | 2021-08-27 | — | — | CN | claimed |
| CN-111205218-A | Photo-initiated aldehyde removal method | 广州中医药大学(广州中医药研究院) | 2020-05-29 | — | — | CN | claimed |
| CN-111205218-B | Photo-initiated aldehyde removal method | 广州中医药大学(广州中医药研究院) | 2021-08-27 | — | — | CN | disclosed |
| CN-111205218-A | Photo-initiated aldehyde removal method | 广州中医药大学(广州中医药研究院) | 2020-05-29 | — | — | CN | disclosed |
| WO-2005037196-A2 | SUBSTITUTED 2-ARYLMETHYLENE-N-ARYL-N'-ARYL-MALONAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA, INC. (US) | 2005-04-28 | — | — | WO | disclosed |