Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249465 | 0.80 | MAPT (0.58) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9733812 | 0.74 | ALDH1A1 (0.56) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21350984 | 0.71 | MAPT (0.50) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL26424875 | 0.70 | HPGD (0.66) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL12918455 | 0.70 | MAPT (0.54) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL3435564 | 0.69 | MAPT (0.80) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12918466 | 0.69 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL951773 | 0.69 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL12918468 | 0.69 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL953048 | 0.69 | MAPT (0.53) | MAPTKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |