Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592711 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL9148275 | 0.80 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6250229 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5347123 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL9434874 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL9147076 | 0.77 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6742491 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL13198633 | 0.76 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL6249880 | 0.76 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL2464202 | 0.72 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000029022-A1 | COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | claimed |
| WO-1998050075-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| WO-2005046650-A1 | PHARMACEUTICAL FORMULATION CONTAINING MUSCLE RELAXANT AND COX-II INHIBITOR | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005044227-A1 | TOPICAL PHARMACEUTICAL COMPOSITIONS | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-05-19 | — | — | WO | disclosed |
| US-20050100594-A1 | Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-05-12 | — | — | US | disclosed |
| US-20050096371-A1 | Topical pharmaceutical compositions | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-05-05 | — | — | US | disclosed |
| US-20040204413-A1 | Pharmaceutical compositions containing a COX-II inhibitor and a muscle relaxant | OSMOTICA CORP. (VG) | 2004-10-14 | — | — | US | disclosed |
| EP-1362585-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING A COX-II INHIBITOR AND A MUSCLE RELAXANT | Osmotica Corp. (VG) | 2003-11-19 | — | — | EP | disclosed |
| EP-1146905-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | Algos Pharmaceutical Corporation (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000029022-A1 | COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000029023-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-1998050075-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5409944-A | Enzyme inhibitors, antiinflammatory agent, antiseptic agent | MERCK FROSST CANADA, INC. (CA) | 1995-04-25 | — | — | US | disclosed |