Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198633 | 0.82 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL6247997 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL11177396 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5347123 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL29385521 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL2464202 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL14280453 | 0.74 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL6742491 | 0.73 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL6249880 | 0.73 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL9535611 | 0.71 | PTGS2 (0.56) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1146905-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | Algos Pharmaceutical Corporation (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000029023-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | claimed |
| WO-1998050075-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-11-12 | — | — | WO | claimed |
| WO-2005046650-A1 | PHARMACEUTICAL FORMULATION CONTAINING MUSCLE RELAXANT AND COX-II INHIBITOR | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005044227-A1 | TOPICAL PHARMACEUTICAL COMPOSITIONS | GLENMARK PHARMACEUTICALS LIMITED (US) | 2005-05-19 | — | — | WO | disclosed |
| US-20050100594-A1 | Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-05-12 | — | — | US | disclosed |
| US-20050096371-A1 | Topical pharmaceutical compositions | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2005-05-05 | — | — | US | disclosed |
| EP-1146905-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | Algos Pharmaceutical Corporation (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000029022-A1 | COX-2 INHIBITORS IN COMBINATION WITH CENTRALLY ACTING ANALGESICS | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-2000029023-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 2000-05-25 | — | — | WO | disclosed |
| WO-1998050075-A1 | COX-2 INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5409944-A | Enzyme inhibitors, antiinflammatory agent, antiseptic agent | MERCK FROSST CANADA, INC. (CA) | 1995-04-25 | — | — | US | disclosed |