Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.73 |
| ▸ | MGAM | O43451 | 3/20 | 0.66 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850641 | 0.84 | RORC (1.00) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL7888385 | 0.83 | MGAM (0.73) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL23851325 | 0.83 | RORC (1.00) | RORCMGAMAMY1AMAPTSMN1; SMN2 | |
| SCHEMBL23851337 | 0.83 | RORC (1.00) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL3802984 | 0.82 | RORC (0.68) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL4080130 | 0.82 | RORC (0.68) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL3801324 | 0.82 | RORC (0.68) | RORCMGAMAMY1AMAPTKDM4E | |
| Bicarbonate SCHEMBL7890907 | 0.81 | RORC (0.67) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL7890904 | 0.81 | RORC (0.67) | RORCMGAMAMY1AMAPTKDM4E | |
| SCHEMBL23850790 | 0.80 | RORC (1.00) | RORCMGAMAMY1AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |