Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 5/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | BRD1 | O95696 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834990 | 0.97 | SGK1 (0.54) | SGK1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL4842115 | 0.93 | TBK1 (0.49) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL4842204 | 0.82 | TBK1 (0.44) | HSPD1PTPN2PTPN1PTPN5HSPE1 | |
| SCHEMBL6247592 | 0.80 | TBK1 (0.47) | TBK1MAPTMEN1ALDH1A1LMNA | |
| SCHEMBL4833765 | 0.80 | TBK1 (0.57) | TBK1MAPTLMNAGAAHTT | |
| SCHEMBL4843803 | 0.76 | TP53 (0.46) | SGK1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL4841855 | 0.74 | MEN1 (0.56) | TBK1TP53MAPTMEN1ALDH1A1 | |
| SCHEMBL4838253 | 0.72 | TSHR (0.47) | TBK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL526830 | 0.69 | SGK1 (0.56) | SGK1HSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL7367756 | 0.67 | MAP2K4 (0.47) | SGK1HSPD1PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004016611-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | disclosed |