Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663781 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL9828880 | 0.88 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL9829428 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL9829421 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL5224258 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL1461981 | 0.83 | ATM (0.60) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL11491274 | 0.83 | ATM (0.60) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL13387483 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL13506655 | 0.82 | NPSR1 (0.58) | SMN1; SMN2RAB9ANPC1LMNACTSK | |
| SCHEMBL7357011 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1LMNACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575914-A1 | AROMATIC DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Procyon Biopharma Inc. (CA) | 2005-09-21 | — | — | EP | disclosed |
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |
| WO-2004056764-A1 | AROMATIC DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PROCYON BIOPHARMA INC. (CA) | 2004-07-08 | — | — | WO | disclosed |