Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218909 | 0.84 | IKBKB (0.38) | IKBKBGPR6 | |
| SCHEMBL6221153 | 0.81 | IKBKB (0.44) | IKBKBCHUKAAK1GPR6ALDH1A1 | |
| SCHEMBL6218845 | 0.76 | GPR6 (0.36) | IKBKBGPR6ALDH1A1L3MBTL1HTT | |
| SCHEMBL6248847 | 0.75 | IKBKB (0.48) | IKBKBCHUKAAK1GPR6ALDH1A1 | |
| SCHEMBL6248851 | 0.75 | IKBKB (0.48) | IKBKBCHUKAAK1GPR6ALDH1A1 | |
| SCHEMBL6248849 | 0.75 | IKBKB (0.48) | IKBKBCHUKAAK1GPR6ALDH1A1 | |
| SCHEMBL6247991 | 0.67 | PTGDR (0.38) | IKBKBCHUKGPR6ALDH1A1L3MBTL1 | |
| SCHEMBL6247985 | 0.67 | PTGDR (0.38) | IKBKBCHUKGPR6ALDH1A1L3MBTL1 | |
| SCHEMBL6247984 | 0.67 | PTGDR (0.38) | IKBKBCHUKGPR6ALDH1A1L3MBTL1 | |
| SCHEMBL23717048 | 0.64 | CYP11B1 (0.47) | IKBKBCHUKCYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |