Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218909 | 0.91 | IKBKB (0.38) | GPR6HRH1CCR3IKBKB | |
| SCHEMBL6218839 | 0.76 | PTGDR (0.42) | GPR6ALDH1A1L3MBTL1CYP2D6IKBKB | |
| SCHEMBL6249262 | 0.76 | IKBKB (0.42) | GPR6ALDH1A1HTTL3MBTL1IKBKB | |
| SCHEMBL6362089 | 0.75 | PTGDR (0.41) | GPR6ALDH1A1L3MBTL1CYP2D6IKBKB | |
| SCHEMBL27623158 | 0.73 | PKM (0.47) | IKBKB | |
| Hydrochloric Acid SCHEMBL2774596 | 0.72 | DPP4 (0.48) | GPR6IKBKB | |
| SCHEMBL2773855 | 0.71 | CCR1 (0.48) | GPR6LMNAHRH1CCR3IKBKB | |
| SCHEMBL6218902 | 0.71 | PTGDR (0.42) | GPR6ALDH1A1L3MBTL1IKBKB | |
| SCHEMBL6104086 | 0.70 | PTGDR (0.45) | GPR6ALDH1A1HRH1CCR3IKBKB | |
| SCHEMBL2773558 | 0.70 | GPR119 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |