Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717484 | 0.88 | PDE4A (0.44) | CYP11B1CYP11B2CYP19A1PDE4AMKNK1 | |
| SCHEMBL23717043 | 0.85 | ROCK2 (0.39) | CYP11B1CYP11B2CYP19A1PDE4AROCK1 | |
| SCHEMBL26525656 | 0.84 | HRH1 (0.49) | PDE4AIKBKBCHUKLCKROCK1 | |
| SCHEMBL23685090 | 0.77 | KMO (0.52) | CYP11B1CYP11B2CYP19A1PDE4AMKNK1 | |
| SCHEMBL23685091 | 0.77 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1PDE4AMKNK1 | |
| SCHEMBL24345432 | 0.72 | HTR2C (0.45) | PDE4AACHE | |
| SCHEMBL26239879 | 0.72 | AKR1C3 (0.51) | CYP11B1CYP11B2CYP19A1MKNK1MKNK2 | |
| SCHEMBL13380078 | 0.72 | AKR1C3 (0.51) | CYP11B1CYP11B2MKNK1MKNK2AKR1C3 | |
| SCHEMBL12263199 | 0.71 | AKR1C3 (0.72) | CYP11B1CYP11B2AKR1C3AKR1C2ADRA2B | |
| SCHEMBL20173750 | 0.70 | AKR1C3 (0.53) | MKNK1MKNK2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | VIP, ACE, FURIN | CYP11B1 174/4885CYP11B2 166/4885CYP19A1 2185/4885 |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | CYP11B1 174/4885CYP11B2 166/4885CYP19A1 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.