Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249304 | 1.00 | CA12 (0.43) | CA12CA1CA7CA14CTSK | |
| SCHEMBL3867978 | 0.88 | NPC1 (0.42) | CA1CTSKCTSSAKT1IDO1 | |
| SCHEMBL13906650 | 0.77 | LMNA (0.44) | CA12CA1CA7CA14 | |
| SCHEMBL8434086 | 0.76 | CA12 (0.48) | CA12CA1 | |
| SCHEMBL17844739 | 0.76 | CA12 (0.47) | CA12CA1CA7CA14CTSK | |
| SCHEMBL17844742 | 0.76 | CA12 (0.47) | CA12CA1CA7CA14CTSK | |
| SCHEMBL19562463 | 0.76 | PPARA (0.37) | CA12CA1CA7CA14CTSK | |
| SCHEMBL31536313 | 0.76 | SYK (0.41) | CA12CA1CA7CA14CTSS | |
| SCHEMBL8837533 | 0.75 | CA12 (0.49) | CA12CA1CA7CA14CTSK | |
| SCHEMBL26831798 | 0.75 | TDP1 (0.34) | CA12CA1CA7CA14CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |