Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966733 | 0.85 | CA12 (0.47) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL5041887 | 0.84 | CA12 (0.51) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL7881460 | 0.82 | PPARA (0.52) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL8577215 | 0.77 | CTSK (0.52) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL7709972 | 0.77 | SYK (0.50) | CA12CA1CA7CA14CTSS | |
| SCHEMBL6610543 | 0.77 | PPARA (0.47) | CA12CA1CA7CA14CTSS | |
| SCHEMBL4583683 | 0.77 | POLB (0.65) | SIGMAR1CTSKKMT2AL3MBTL1POLB | |
| SCHEMBL572740 | 0.76 | IDO1 (0.60) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL9608852 | 0.76 | SIGMAR1 (0.46) | CA12CA1CA7CA14SIGMAR1 | |
| SCHEMBL4961185 | 0.76 | SIGMAR1 (0.62) | SIGMAR1KMT2APOLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |