Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439630 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL29987688 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL1201242 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL902111 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| Hydrochloric Acid SCHEMBL2870378 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL26002434 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL24343243 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL9564928 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL22059185 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL22651899 | 0.71 | ESR1 (0.40) | ALDH1A1KDM4EKMT2APOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560865-A1 | POLYURETHANE COMPOUNDS AND ARTICLES PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041899-A1 | POLYURETHANE COMPOUNDS AND ARTICLES PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087754-A1 | Polyurethane compounds and articles prepared therefrom | FOLEY PAUL (US) | 2004-05-06 | — | — | US | disclosed |