Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250293 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL6250787 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA4SMN1; SMN2EPHX1ALOX15 | |
| SCHEMBL6250594 | 0.78 | ACHE (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL6250767 | 0.77 | ACHE (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| Methacrylic Acid SCHEMBL28459771 | 0.76 | GAA (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| Methacrylic Acid SCHEMBL29020791 | 0.76 | GAA (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL6252109 | 0.75 | ACHE (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4EPHX1 | |
| SCHEMBL2378401 | 0.74 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL22279136 | 0.72 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL810364 | 0.72 | EGLN1 (0.41) | ALDH1A1SMN1; SMN2KMT2AACHEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047234-A1 | METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS | Röhm GmbH & Co. KG (DE) | 2005-05-26 | — | — | WO | disclosed |