Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 10/20 | 0.41 |
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249483 | 1.00 | OGA (0.43) | OGANPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL5725535 | 0.88 | FLT3 (0.46) | OGANPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL5725547 | 0.88 | FLT3 (0.46) | OGANPC1RAB9ASMN1; SMN2ADORA3 | |
| SCHEMBL6249237 | 0.83 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL6249236 | 0.83 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL6248651 | 0.82 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2TSHRLMNA | |
| SCHEMBL6248648 | 0.82 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2TSHRLMNA | |
| SCHEMBL6246897 | 0.81 | CDK2 (0.47) | OGANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6250143 | 0.81 | CCNB2 (0.47) | RAB9ASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6246901 | 0.81 | CDK2 (0.47) | OGANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | claimed |
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |