Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249236 | 1.00 | KMT2A (0.43) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6248648 | 0.89 | RAB9A (0.46) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6248651 | 0.89 | RAB9A (0.46) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5725377 | 0.87 | CDK2 (0.49) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5725385 | 0.87 | CDK2 (0.49) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6249487 | 0.83 | OGA (0.43) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6249483 | 0.83 | OGA (0.43) | KMT2AMEN1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6249800 | 0.81 | OGA (0.41) | KMT2AMEN1MAPTCDK2CCNE1 | |
| SCHEMBL6249797 | 0.81 | OGA (0.41) | KMT2AMEN1MAPTCDK2CCNE1 | |
| SCHEMBL6246897 | 0.81 | CDK2 (0.47) | KMT2AMEN1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | claimed |