SCHEMBL6249683

SCHEMBL6249683

O=C1CCC2=CC=C3C=CCCC3C2C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6249751 0.77 CYP19A1 (0.32) CYP19A1
SCHEMBL11702792 0.75
SCHEMBL821855 0.75
Hydrazine SCHEMBL1572402 0.72 KDM1A (0.30)
SCHEMBL9430980 0.69 MAPT (0.40) CYP19A1
SCHEMBL31097915 0.65
SCHEMBL11817035 0.59
SCHEMBL11189349 0.59
SCHEMBL25567223 0.58
SCHEMBL13370025 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399406-B1 NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I KAROBIO AB (SE) 2005-08-10 EP claimed
WO-2002053522-A2 NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I KARO BIO AB (SE) 2002-07-11 WO claimed
EP-1399406-B1 NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I KAROBIO AB (SE) 2005-08-10 EP disclosed