Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097915 | 0.73 | — | — | |
| SCHEMBL11702792 | 0.72 | — | — | |
| SCHEMBL821855 | 0.72 | — | — | |
| SCHEMBL6247864 | 0.72 | MAPT (0.36) | MAPT | |
| Hydrazine SCHEMBL1572402 | 0.70 | KDM1A (0.30) | — | |
| SCHEMBL6249751 | 0.69 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL6249683 | 0.69 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL11817035 | 0.67 | — | — | |
| SCHEMBL11189349 | 0.67 | — | — | |
| SCHEMBL28399318 | 0.64 | MAPT (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356935-A | Reductase inhibitors | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |