Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RHOC | P08134 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247042 | 0.91 | JUN (0.41) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6250718 | 0.89 | JUN (0.42) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6247803 | 0.83 | JUN (0.42) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6249568 | 0.82 | PI4KB (0.45) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6365689 | 0.81 | JUN (0.43) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6245874 | 0.80 | SMN1; SMN2 (0.49) | NFKB1LMNATP53DHODH | |
| SCHEMBL6683045 | 0.76 | PI4KB (0.45) | JUNNFKB1NFKB2RELAPI4KB | |
| SCHEMBL6245913 | 0.72 | KCNQ3 (0.56) | LMNAP2RX1DHODHMAPT | |
| SCHEMBL27935938 | 0.72 | MAPT (0.46) | RAF1BRAFKCNH2LMNAMAPT | |
| SCHEMBL7230088 | 0.69 | POLB (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041665-A1 | INSECTICIDAL PERFLUOROALKYLTHIAZOLE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | NIPPON SODA CO., LTD. | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | FFAR3, CYP4F3, NPFFR1 | JUN 3855/4885NFKB1 3016/4885NFKB2 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.