Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | XPO1 | O14980 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247803 | 0.91 | JUN (0.42) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6677807 | 0.88 | TRPV1 (0.51) | PI4KB | |
| SCHEMBL7240089 | 0.87 | P2RX1 (0.53) | LMNAP2RX1GAARXFP1MAPT | |
| SCHEMBL6249568 | 0.77 | PI4KB (0.45) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6365689 | 0.76 | JUN (0.43) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6247042 | 0.76 | JUN (0.41) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6249727 | 0.76 | JUN (0.41) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6250718 | 0.75 | JUN (0.42) | PI4KBHDAC3HDAC8HDAC6RAF1 | |
| SCHEMBL6680901 | 0.74 | CASP3 (0.54) | LMNATP53NFKB1NFKB2RELA | |
| SCHEMBL6229445 | 0.74 | NPC1 (0.67) | RAF1BRAFKCNH2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056177-A2 | INSECTICIDAL AMINOTHIAZOLE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2004-07-08 | — | — | WO | disclosed |
| US-6737382-B1 | WIDE SPECTRUM OF PLANT PROTECTING ACTIVITY | NIPPON SODA CO. LTD. (JP) | 2004-05-18 | — | — | US | disclosed |
| US-20040082629-A1 | INSECTICIDAL AMINOTHIAZOLE DERIVATIVES | NIPPON SODA CO., LTD. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082629-A1 | INSECTICIDAL AMINOTHIAZOLE DERIVATIVES | SCN7A, SCN2B, CASP7 | PI4KB 4070/4885HDAC3 366/4885HDAC8 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.