Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 11/20 | 0.50 |
| ▸ | CDK2 | P24941 | 11/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.50 |
| ▸ | CCND2 | P30279 | 1/20 | 0.50 |
| ▸ | CCND3 | P30281 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 6/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250263 | 1.00 | CCNE1 (0.50) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725374 | 0.89 | CDK2 (0.62) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725115 | 0.89 | CCNE1 (0.49) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725122 | 0.89 | CCNE1 (0.49) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725069 | 0.89 | CDK2 (0.62) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725059 | 0.89 | CDK2 (0.62) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL6248651 | 0.82 | RAB9A (0.46) | CCNE1CDK2CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL6248648 | 0.82 | RAB9A (0.46) | CCNE1CDK2CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL6250103 | 0.81 | CCNE1 (0.55) | CCNE1CDK2CDK1CDK4CCNB1 | |
| SCHEMBL5725166 | 0.78 | CDK2 (0.60) | CCNE1CDK2CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | claimed |
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |