Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 12/20 | 0.55 |
| ▸ | CDK2 | P24941 | 12/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.55 |
| ▸ | CDK1 | P06493 | 3/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.55 |
| ▸ | CCND1 | P24385 | 3/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.55 |
| ▸ | CCND2 | P30279 | 1/20 | 0.55 |
| ▸ | CCND3 | P30281 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.52 |
| ▸ | GLS | O94925 | 6/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CCNH | P51946 | 1/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503715 | 0.87 | CCNE1 (0.72) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL6250265 | 0.81 | CCNE1 (0.50) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL6250263 | 0.81 | CCNE1 (0.50) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL20014229 | 0.78 | CCNE1 (0.62) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL5835963 | 0.78 | CCNE1 (0.58) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL20014231 | 0.78 | CCNE1 (0.58) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL5836526 | 0.77 | CCNE1 (0.64) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL27578137 | 0.73 | CCNE1 (0.76) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL13694242 | 0.73 | GLS (0.59) | CCNE1CDK2CCNE2CDK1CDK4 | |
| SCHEMBL20014219 | 0.73 | CCNE1 (0.52) | CCNE1CDK2CCNE2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | claimed |
| WO-2005035541-A1 | SILICON COMPOUNDS AND THEIR USE | AMEDIS PHARMACEUTICALS LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |