Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784042 | 0.79 | CHRM2 (0.46) | LIPGLIPEFFAR4ENPP2TSHR | |
| SCHEMBL3314900 | 0.78 | ALDH1A1 (0.39) | LIPGALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL3789584 | 0.78 | CYP1A2 (0.40) | LIPGALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL1991553 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL3786211 | 0.71 | CYP1A2 (0.47) | LIPGALDH1A1KMT2AMAPTLIPE | |
| Ammonia Solution, Strong SCHEMBL8858388 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL3982711 | 0.70 | KDM4E (0.45) | LIPGALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL9751833 | 0.70 | SCN8A (0.41) | LIPGALDH1A1KMT2ALTA4HMEN1 | |
| SCHEMBL3781870 | 0.70 | CYP1A2 (0.50) | LIPGALDH1A1KDM4EGAATLR4 | |
| SCHEMBL3316363 | 0.70 | THRA (0.42) | LIPGALDH1A1KMT2AKDM4ELPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505968-A1 | MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097047-A1 | MULTICYCLIC COMPOUNDS FOR USE AS MELANIN CONCENTRATING HORMONE ANTAGONISTS IN THE TREATMENT OF OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2003-11-27 | — | — | WO | disclosed |