SCHEMBL6250404

SCHEMBL6250404

C=C(C)C(=O)OC(O)CC.C=CC(=O)OC(O)CC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.35
HPGD P15428 1/20 0.34
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL12150071 0.95 TSHR (0.33) TSHRHPGDALDH1A1THRB
SCHEMBL21313306 0.94 TSHR (0.35) TSHRHPGDTHRB
SCHEMBL9853354 0.92 TSHR (0.36) TSHRHPGDALDH1A1THRB
SCHEMBL5090391 0.92 TSHR (0.36) TSHRHPGDALDH1A1THRB
SCHEMBL28131551 0.90 ALDH1A1 (0.48) TSHRHPGDALDH1A1THRB
SCHEMBL6368772 0.89 THRB (0.41) TSHRHPGDALDH1A1THRB
Methacrylic Acid SCHEMBL27350263 0.88 TSHR (0.33) TSHR
Methacrylic Acid SCHEMBL27860428 0.88 TSHR (0.36) TSHRHPGDALDH1A1THRB
Methacrylic Acid SCHEMBL8653005 0.88 TSHR (0.36) TSHRHPGDALDH1A1THRB
Acrylic Acid SCHEMBL11779134 0.88 TSHR (0.36) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005035601-A1 FORMALDEHYDE FREE INSULATION BINDER GEORGIA-PACIFIC RESINS, INC. (US) 2005-04-21 WO claimed
US-20050059770-A1 Formaldehyde free insulation binder GEORGIA-PACIFIC RESINS CORPORATION (US) 2005-03-17 US claimed
EP-0620455-B1 Polymeric ophthalmic lens with crosslinker containing saccharide residue JOHNSON & JOHNSON VISION PROD (US) 2000-12-20 EP claimed
US-5690953-A SOFT HYDROGEL CONTACT LENSES JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1997-11-25 US claimed
EP-0620455-A2 Polymeric ophthalmic lens with crosslinker containing saccharide residue JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1994-10-19 EP claimed
EP-0566801-B1 Organic solvent and water resistant, thermally, oxidatively and hydrolytically stable radiation-curable coatings for optical fibers, optical fibers coated therewith and processes for making same BORDEN INC (US) 1998-12-30 EP disclosed
US-5587403-A ACRYLATED POLYETHERURETHANE COPOLYMER BORDEN, INC. (US) 1996-12-24 US disclosed
US-5538791-A BASED ON A POLYETHER POLYOL-BASED REACTIVELY TERMINATED ALIPHATIC URETHANE OLIGOMER BORDEN, INC. (US) 1996-07-23 US disclosed
US-5527835-A CURABLE ACRYLATED POLYETHERURETHANE WITH ACRYLATE MONOMERS, SILANE COUPLER AND PHOTOINITIATOR BORDEN, INC. (US) 1996-06-18 US disclosed
EP-0566801-A2 Organic solvent and water resistant, thermally, oxidatively and hydrolytically stable radiation-curable coatings for optical fibers, optical fibers coated therewith and processes for making same BORDEN, INC. (US) 1993-10-27 EP disclosed
US-4656218-A CASEIN PROTECTIVE COLLOIDS SANYO KOKUSAKU PULP CO., LTD. (JP) 1987-04-07 US disclosed
US-4645783-A BLEND CONTAINING CASEIN SANYO KOKUSAKU PULP CO. (JP) 1987-02-24 US disclosed
US-4242242-A POLYMERS OF 2-ACRYLAMIDO-2-METHYL-1-PROPANESULFONIC ACID AKZONA INCORPORATED (US) 1980-12-30 US disclosed