Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368437 | 1.00 | NPSR1 (0.48) | NPSR1POLBTDP1MAPTKMT2A | |
| SCHEMBL21368257 | 0.84 | TSHR (0.41) | NPSR1POLBTDP1ALDH1A1TSHR | |
| SCHEMBL21367972 | 0.83 | TAS1R3 (0.55) | POLBTSHRTAS1R3TAS1R1NOS3 | |
| SCHEMBL29820642 | 0.83 | TAS1R3 (0.55) | POLBTSHRTAS1R3TAS1R1NOS3 | |
| SCHEMBL16964411 | 0.83 | TSHR (0.40) | NPSR1POLBTDP1MAPTKMT2A | |
| SCHEMBL21368436 | 0.81 | TSHR (0.46) | POLBALDH1A1TSHRTAS1R3TAS1R1 | |
| SCHEMBL21368435 | 0.81 | PPID (0.46) | TSHRTAS1R3TAS1R1NOS3NOS1 | |
| SCHEMBL21675512 | 0.80 | CTSK (0.61) | NPSR1POLBTDP1MAPTKMT2A | |
| SCHEMBL27513177 | 0.79 | NPSR1 (0.51) | NPSR1POLBTDP1MAPTKMT2A | |
| SCHEMBL21368254 | 0.78 | TSHR (0.50) | NPSR1POLBTDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560630-A2 | 7H-DIBENZO[B,G][1,5]DIOXOCIN-5-ONE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004039453-A2 | 7H-DIBENZO[B,G][1,5]DIOXOCIN-5-ONE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2004-05-13 | — | — | WO | disclosed |