SCHEMBL6250992

SCHEMBL6250992

C=C(C)C(=O)O[SiH2]O[SiH2]O[SiH2]O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6254900 1.00 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL6254998 1.00 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL829058 0.87
SCHEMBL6907374 0.79
SCHEMBL11620874 0.79
Methacrylic Acid SCHEMBL12501960 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL261665 0.78 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL9254205 0.77
SCHEMBL11616134 0.76
SCHEMBL11131490 0.72 ALDH1A1 (0.68) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088564-A1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS DSM IP ASSETS B.V. (NL) 2017-03-30 US disclosed
EP-2670757-B1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS DSM IP ASSETS BV (NL) 2015-05-27 EP disclosed
US-20140135408-A1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS DSM IP ASSETS B.V. (NL) 2014-05-15 US disclosed
EP-2670757-A1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS DSM IP Assets B.V. (NL) 2013-12-11 EP disclosed
WO-2012104349-A1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS DSM IP ASSETS B.V. (NL) 2012-08-09 WO disclosed
EP-1572702-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2005-09-14 EP disclosed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP disclosed
WO-2004056838-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2004-07-08 WO disclosed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088564-A1 SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS HRH3, HRH1, H1-3 ALDH1A1 2406/4885TSHR 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.