SCHEMBL261665

SCHEMBL261665

C=C(C)C(=O)O[SiH2]OC(=O)C(=C)C

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 2/20 0.38
THRB P10828 1/20 0.38
HSD17B10 Q99714 1/20 0.35
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27718680 0.92 ALDH1A1 (0.46) ALDH1A1TSHRTDP1THRBHSD17B10
SCHEMBL10340727 0.87
SCHEMBL829058 0.85
SCHEMBL13685616 0.84 ALDH1A1 (0.39) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL2961857 0.83 ALDH1A1 (0.42) ALDH1A1TSHRTDP1THRB
SCHEMBL28565199 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL4979158 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL29151765 0.81 THRB (0.44) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL28411732 0.80
SCHEMBL305992 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2033990-B2 NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORP (JP) 2020-08-12 EP disclosed
US-9163132-B2 Nitrile rubber composition, cross-linkable nitrile rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2015-10-20 US disclosed
EP-2033990-B1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORP (JP) 2013-06-12 EP disclosed
US-8133948-B2 Nitrile rubber composition, cross-linkable nitrile rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2012-03-13 US disclosed
US-20120041127-A1 NITRILE RUBBER COMPOSITION, CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER NAGAMORI HIROYASU (JP) 2012-02-16 US disclosed
US-20090234054-A1 NITRILE RUBBER COMPOSITION, CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2009-09-17 US disclosed
EP-2033990-A1 NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORPORATION (JP) 2009-03-11 EP disclosed