Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | NMBR | P28336 | 1/20 | 0.34 |
| ▸ | GRPR | P30550 | 1/20 | 0.34 |
| ▸ | PLTP | P55058 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994303 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTNPSR1FPR1NMBR | |
| SCHEMBL6255331 | 0.89 | MEN1 (0.34) | ALDH1A1MAPTNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL6252251 | 0.88 | NMBR (0.48) | FPR1NMBRGRPR | |
| SCHEMBL6251353 | 0.83 | MEN1 (0.35) | ALDH1A1VCPMEN1KMT2A | |
| SCHEMBL6253307 | 0.81 | TACR1 (0.41) | MAPTFPR1NMBRGRPR | |
| SCHEMBL6251024 | 0.80 | NMBR (0.55) | ALDH1A1MAPTNPSR1FPR1NMBR | |
| SCHEMBL6254936 | 0.80 | NMBR (0.55) | ALDH1A1MAPTNPSR1FPR1NMBR | |
| SCHEMBL6253540 | 0.78 | NMBR (0.38) | MAPTFPR1NMBRGRPR | |
| SCHEMBL6252297 | 0.77 | NMBR (0.48) | MAPTFPR1NMBRGRPRMEN1 | |
| SCHEMBL6990221 | 0.77 | NMBR (0.48) | MAPTFPR1NMBRGRPRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | claimed |
| US-20040110768-A1 | Bombesin receptor antagonists | WARNER-LAMBERT COMPANY LLC | 2004-06-10 | — | — | US | claimed |
| US-20020169101-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY | 2002-11-14 | — | — | US | claimed |
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |
| US-20040110768-A1 | Bombesin receptor antagonists | WARNER-LAMBERT COMPANY LLC | 2004-06-10 | — | — | US | disclosed |
| US-20040087561-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY LLC | 2004-05-06 | — | — | US | disclosed |
| US-20020169101-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY | 2002-11-14 | — | — | US | disclosed |
| US-20020058606-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058606-A1 | Treatment of sexual dysfunction | BRS3, GNRHR, VIPR2 | ALDH1A1 4719/4885MAPT 4579/4885NPSR1 20/4885 |
| US-20040110768-A1 | Bombesin receptor antagonists | NPY1R, BDKRB1, NPY2R | ALDH1A1 4738/4885MAPT 4546/4885NPSR1 23/4885 |
| US-20040087561-A1 | Treatment of sexual dysfunction | BRS3, MME, ECE1 | ALDH1A1 3614/4885MAPT 4738/4885NPSR1 43/4885 |
| US-20020169101-A1 | Treatment of sexual dysfunction | BRS3, MME, ECE1 | ALDH1A1 3614/4885MAPT 4738/4885NPSR1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.