Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 13/20 | 0.55 |
| ▸ | GRPR | P30550 | 13/20 | 0.55 |
| ▸ | FPR1 | P21462 | 5/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251024 | 1.00 | NMBR (0.55) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6255326 | 0.90 | NMBR (0.51) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6810082 | 0.88 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6252249 | 0.88 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6251350 | 0.84 | FPR1 (0.43) | NMBRGRPRFPR1ALDH1A1MAPT | |
| SCHEMBL6810086 | 0.81 | NMBR (0.62) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6253303 | 0.81 | NMBR (0.62) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6251031 | 0.80 | ALDH1A1 (0.37) | NMBRGRPRFPR1ALDH1A1MAPT | |
| SCHEMBL6994303 | 0.80 | ALDH1A1 (0.37) | NMBRGRPRFPR1ALDH1A1MAPT | |
| SCHEMBL6253532 | 0.77 | NMBR (0.58) | NMBRGRPRFPR1AGTR1GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |