Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250112 | 0.85 | DYRK1A (0.61) | SCDSMN1; SMN2MAPTHSD17B10DYRK1A | |
| Hydrochloric Acid SCHEMBL6834656 | 0.84 | DYRK1A (0.60) | SCDSMN1; SMN2MAPTHSD17B10DYRK1A | |
| SCHEMBL9474671 | 0.74 | CYP3A4 (0.67) | SMN1; SMN2MAPTALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL6254947 | 0.72 | DYRK1A (0.60) | SMN1; SMN2MAPTHPGDALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6253890 | 0.71 | DYRK1A (0.59) | SMN1; SMN2MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL9776965 | 0.71 | DYRK1A (0.65) | SMN1; SMN2MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11011397 | 0.71 | MAPT (0.59) | SMN1; SMN2MAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL21682203 | 0.70 | MAPT (0.61) | SCDSMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL7597159 | 0.70 | NPC1 (0.56) | SMN1; SMN2MAPTHPGDALDH1A1DYRK1A | |
| SCHEMBL11191318 | 0.68 | KMT2A (0.73) | SMN1; SMN2MAPTHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569641-A2 | PROPARGYL-TRIFLUOROMETHOXY-AMINO-BENZOTHIAZOLE DERIVATIVES | Teva Pharmaceutical Industries Limited (IL) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004047756-A2 | PROPARGYL-TRIFLUOROMETHOXY-AMINO-BENZOTHIAZOLE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-06-10 | — | — | WO | disclosed |