Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | KDM1A | O60341 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123338 | 0.83 | HTR2C (0.45) | HTR2CKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL6322679 | 0.81 | CHRM2 (0.70) | HTR2CKDM1AMAOAMAOBCHRM2 | |
| SCHEMBL6227345 | 0.80 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL6227343 | 0.80 | HTR2C (0.61) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL6319899 | 0.80 | PDE4A (0.47) | KDM1ACHRM2CHRM1CHRM3TUBB4A | |
| SCHEMBL23995535 | 0.79 | HTR2C (0.69) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL16591278 | 0.79 | HTR2C (0.69) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL2435013 | 0.79 | HTR2C (0.59) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL2091037 | 0.78 | HTR2C (0.62) | HTR2CKDM1AMAOAMAOBDRD2 | |
| SCHEMBL2090322 | 0.78 | HTR2C (0.62) | HTR2CKDM1AMAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051904-A2 | NOVEL PROCESSES FOR THE SYNTHESIS OF CYCLOPROPYL COMPOUNDS | PHARMACIA CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |