Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123174 | 0.85 | CHRM2 (0.52) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL9380891 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL23995531 | 0.81 | HTR2C (0.74) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL20205056 | 0.81 | HTR2C (0.74) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL6251810 | 0.81 | HTR2C (0.61) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL22334915 | 0.81 | HTR2C (0.74) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL6319621 | 0.81 | HTR2A (0.65) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL8097675 | 0.80 | HTR2C (1.00) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL8088821 | 0.80 | HTR2C (0.72) | CHRM2CHRM1CHRM3HTR2CHTR2A | |
| SCHEMBL8097678 | 0.80 | HTR2C (1.00) | CHRM2CHRM1CHRM3HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921767-B2 | Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives | PHARMACIA CORPORATION (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040092538-A1 | Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092538-A1 | Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives | ITGA5, ITGB5, ITGB3 | CHRM2 983/4885CHRM1 766/4885CHRM3 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.