Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653300 | 0.94 | TDP1 (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9540715 | 0.91 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9794612 | 0.91 | TDP1 (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL19323989 | 0.91 | TDP1 (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| Undecane SCHEMBL8665406 | 0.87 | TDP1 (0.44) | ALDH1A1TSHRTDP1KMT2AMEN1 | |
| SCHEMBL12457255 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7672142 | 0.81 | TDP1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2454280 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28088679 | 0.81 | TDP1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5940396 | 0.81 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856315-B1 | PROTEIN-FARNESYLTRANSFERASE INHIBITORS IN COMBINATION WITH HMGCOA-REDUCTASE-INHIBITORS FOR THE TREATMENT OF AIDS | BANYU PHARMA CO LTD (JP) | 2005-08-24 | — | — | EP | disclosed |
| US-6083985-A | LOVASTATIN, SIMVASTATIN, PRAVASTATIN OR FLUVASTATIN OR DERIVATIVES DECREASES FARNESYL PYROPHOSPHATE IN VIVO; PROTEIN-FARNESYLTRANSFERASE INHIBITOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| US-6017956-A | AN ANTITUMOR AGENT, AN ENZYME INHIBITOR FOR INHIBITING PROTEIN-FARNESYL TRANSFERASE TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0776884-B1 | SUBSTITUTED AMIDE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5919786-A | ANTITUMOR AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| US-5849747-A | N, n-disubstituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0856315-A1 | MEDICINAL COMPOSITION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-08-05 | — | — | EP | disclosed |
| EP-0805154-A1 | N,N-DISUBSTITUTED AMIC ACID DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5643958-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0776884-A1 | SUBSTITUTED AMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |