Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9794612 | 0.89 | TDP1 (0.48) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL19323989 | 0.89 | TDP1 (0.48) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL9295748 | 0.85 | TDP1 (0.41) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL9295744 | 0.85 | TDP1 (0.41) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL29055376 | 0.83 | ALDH1A1 (0.39) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL2454280 | 0.83 | MGAM (0.46) | TDP1ALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL6599659 | 0.83 | ALDH1A1 (0.42) | TDP1ALDH1A1MEN1NPC1KMT2A | |
| SCHEMBL28088679 | 0.83 | TDP1 (0.42) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL6668703 | 0.81 | TDP1 (0.41) | TDP1EGLN1ALDH1A1MEN1NPC1 | |
| SCHEMBL6251850 | 0.81 | MGAM (0.44) | TDP1EGLN1ALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980108-B | Preparation method of 2- (1-methyl alkyl) succinic acid | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |
| CN-103980108-A | Preparation method of 2- (1-methyl alkyl) succinic acid | UNIV EAST CHINA SCIENCE & TECH | 2014-08-13 | — | — | CN | disclosed |
| US-6462042-B1 | TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITORS; INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, CANCER, CARDIO-VASCULAR DISEASES, RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, NEURODEGENERATION, ALZHEIMER'S DISEASE, STROKE | DARWIN DISCOVERY LIMITED (GB) | 2002-10-08 | — | — | US | disclosed |
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |