SCHEMBL2454280

SCHEMBL2454280

CCOC(=O)CC(C(=O)OCC)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALDH1A1 P00352 6/20 0.43
ALOX15 P16050 3/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
TRPA1 O75762 1/20 0.43
HSD17B10 Q99714 2/20 0.42
CHRM1 P11229 1/20 0.42
ADORA1 P30542 1/20 0.42
CYP2D6 P10635 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
SOAT1 P35610 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL28133876 0.98 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28870965 0.94 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
Propionitrile SCHEMBL28226679 0.89 GAA (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28135330 0.89 MGAM (0.38) MGAMGAASIMGAM2ALDH1A1
SCHEMBL9540715 0.89 MGAM (0.52) MGAMGAASIMGAM2ALDH1A1
SCHEMBL29636387 0.88 GAA (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL21313402 0.86 ALDH1A1 (0.36) MGAMGAASIMGAM2ALDH1A1
SCHEMBL21313397 0.86 ALDH1A1 (0.39) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27894893 0.86 LMNA (0.40) MGAMGAASIMGAM2ALDH1A1
SCHEMBL2637863 0.85 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-106608933-A Catalyst component for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2017-05-03 CN claimed
CN-106608937-A Catalyst component for olefin polymerization, preparation method and application thereof 中国石油化工股份有限公司 2017-05-03 CN claimed
CN-106608935-A Catalyst components used for olefin polymerization, catalyst and application of catalyst 中国石油化工股份有限公司 2017-05-03 CN claimed
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-15 US disclosed
CN-119630709-A Strain hardening reinforced polypropylene composition and method for producing the same 埃克森美孚化学专利公司 2025-03-14 CN disclosed
CN-119331139-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-119331132-A Catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
WO-2024025741-A1 POLYPROPYLENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-02-01 WO disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
WO-2003076479-A1 PROCESS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-09-18 WO disclosed
US-20030060581-A1 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-03-27 US disclosed
EP-1272533-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.p.A. (IT) 2003-01-08 EP disclosed
WO-2002030998-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2002-04-18 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME PFN1, PSD, FDFT1 MGAM 3563/4885GAA 4596/4885SI 4745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.